October 1, 2016

Tissue-on-a-Chip / Organ-on-a-Chip / Human-on-a-Chip

An organ-on-a-chip is a multi-channel 3-D microfluidic cell culture chip stimulating entire specific tissue for drug screening or molecular analysis purposes. There are also ongoing projects to make whole human-on-a-chip a reality.

The best 3D culture models even fail to mimic an organ’s cellular properties in many aspects. The application of microfluidics in tissue-on-chips enables the efficient transport and distribution of molecules/drugs throughout the viable 3D tissue constructs inside channels.

Mimicking a human’s physiological responses in an in vitro model needs to be made more affordable, and needs to offer cellular level control in biological experiments: biomimetic microfluidic systems could replace animal testing. The development of Lab-on-a-Chip biochips that reproduce complex organ-level pathological responses could revolutionize many fields, including toxicology and the developmental process of pharmaceuticals and cosmetics that rely on animal testing and clinical trials.

Some Tissue-on-Chips examples are as below and we will be glad to help you in this technology;

– Cornea-on-a-Chip
– Kidney-on-a-Chip
– Lung-on-a-Chip
– Heart-on-a-Chip
– Neuron-on-a-Chip
– Your idea :)